One of the Universe’s Most Powerful Events, researchers have made great strides in understanding these explosive bursts, but much of their nature remains a mystery. Firing off at astronomical distances at a startling frequency, GRBs pose a potential existential threat to our civilization, as our planet’s own history might indicate. With the launch of the Fermi Gamma-Ray Space Telescope and the Neil Gehrels Swift Observatory, developments over the past decades, ongoing into the future, aim to enhance our knowledge of this phenomenon.